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Acriflavin for biochemistry

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08048036175

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Hyderabad, India, 500001

Description

Acriflavin for biochemistry is a high-purity, laboratory-grade red or reddish-brown crystalline compound commonly used as a fluorescent dye, biological stain, and antimicrobial agent in biochemical and microbiological research.​ Chemical Properties Chemical Name: Acriflavin (often supplied as acriflavine hydrochloride).​ Molecular Formula: C₁₄H₁₄N₃Cl.​ Molecular Weight: 259.74 g/mol.​ CAS Number: 8048-52-0 or 8063-24-9.​ Appearance: Red or orange-red crystalline powder.​ Purity (Assay): 98.5–105% on dry/anhydrous basis.​ Solubility: Soluble in water and alcohol.​ Sulphated Ash: Max. 1.0% w/w.​ Water Content: Max. 6.5% w/w.​ pH (aqueous solution): Neutral to slightly acidic.​ Principal Applications in Biochemistry Fluorescent Staining: Used for fluorescent labeling and staining of nucleic acids (DNA, RNA) and proteins, facilitating their visualization in gel electrophoresis and fluorescence microscopy.​ Antimicrobial Agent: Acts as a topical antiseptic and antimicrobial agent for wound treatment, laboratory culture disinfection, and as an antiviral/antifungal compound in various biological models.​ Biological Research: Intercalates into DNA, inhibiting bacterial and viral replication, and is used to study nucleic acid behavior, cell cycle dynamics, and gene expression.​ Cancer and Drug Resistance Research: Investigated for its ability to inhibit HIF-1α (Hypoxia inducible factor) and sensitize cancer cells to therapy—an emerging area in biomedical research.​ Safety and Handling Acriflavin is poisonous and may irritate eyes, skin, and the respiratory system; appropriate PPE is required during laboratory handling.​ Should be stored in a cool, dry place, away from direct sunlight and moisture for maximum shelf life.​ Stains skin and surfaces easily and requires care in use and cleanup

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